Serum concentrations of free ubiquitin and multiubiquitin chains
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چکیده
منابع مشابه
Serum concentrations of free ubiquitin and multiubiquitin chains.
Ubiquitin, which can conjugate with cellular proteins, is classified into two forms: free ubiquitin and multiubiquitin chains. The latter is active as a signal for degradation of the targeted proteins. We found both forms in human serum and, using two immunoassays, quantitated them in sera from healthy subjects and patients with some diseases. Because of putative leakage of erythrocyte ubiquiti...
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Although the normal thyroid gland secretes both levothyroxine (L-T4) and levotriiodothyronine (L-T3), normalization of serum TSH with L-T4-replacement therapy alone in hypothyroidism is generally believed to result in a normal serum L-T3 and to reflect a euthyroid state. However several recent studies suggest that this may not be the case. Accordingly, the relationship between serum free L-T4 a...
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References 1. Bry L, Chen PC, Sacks DB. Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin [Review]. Clin Chem 2001;47:153–63. 2. Sacks DB. Hemoglobin variants and hemoglobin A1c analysis: problem solved? [Editorial]. Clin Chem 2003;49:1245–7. 3. Watanabe T, Kato K, Yamada D, Midorikawa S, Sato W, Shiga M, et al. A nondiabetic case of hemoglobin var...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1997
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/43.7.1188